Dependence of T Cell Antigen Recognition on T Cell Receptor-Peptide MHC Confinement Time

T cell receptor (TCR) binding to diverse peptide-major histocompatibility complex (pMHC) ligands results in various degrees of T cell activation. Here we analyze which binding properties of the TCR-pMHC interaction are responsible for this variation in pMHC activation potency. We have analyzed activ...

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Detalles Bibliográficos
Autores principales: Aleksic, Milos, Dushek, Omer, Zhang, Hao, Shenderov, Eugene, Chen, Ji-Li, Cerundolo, Vincenzo, Coombs, Daniel, van der Merwe, P. Anton
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862301/
https://www.ncbi.nlm.nih.gov/pubmed/20137987
http://dx.doi.org/10.1016/j.immuni.2009.11.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862301/
https://www.ncbi.nlm.nih.gov/pubmed/20137987
http://dx.doi.org/10.1016/j.immuni.2009.11.013

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