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Dependence of T Cell Antigen Recognition on T Cell Receptor-Peptide MHC Confinement Time
T cell receptor (TCR) binding to diverse peptide-major histocompatibility complex (pMHC) ligands results in various degrees of T cell activation. Here we analyze which binding properties of the TCR-pMHC interaction are responsible for this variation in pMHC activation potency. We have analyzed activ...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862301/ https://www.ncbi.nlm.nih.gov/pubmed/20137987 http://dx.doi.org/10.1016/j.immuni.2009.11.013 |