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Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumors after a single injection
New strategies to self-assemble biocompatible materials into nanoscale, drug-loaded packages with improved therapeutic efficacy are needed for nanomedicine. To address this need, we developed artificial recombinant chimeric polypeptides (CPs) that spontaneously self-assemble into sub-100 nm size, ne...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862348/ https://www.ncbi.nlm.nih.gov/pubmed/19898461 http://dx.doi.org/10.1038/nmat2569 |