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Dissection of genetically complex traits with extremely large pools of yeast segregants

Most heritable traits, including many human diseases 1, are caused by multiple loci. Studies in both humans and model organisms, such as yeast, have failed to detect a large fraction of the loci that underlie such complex traits 2,3. A lack of statistical power to identify multiple loci with small e...

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Detalles Bibliográficos
Autores principales: Ehrenreich, Ian M., Torabi, Noorossadat, Jia, Yue, Kent, Jonathan, Martis, Stephen, Shapiro, Joshua A., Gresham, David, Caudy, Amy A., Kruglyak, Leonid
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862354/
https://www.ncbi.nlm.nih.gov/pubmed/20393561
http://dx.doi.org/10.1038/nature08923