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Uncoupling oxidative/energy metabolism with low sub chronic doses of 3-nitropropionic acid or iodoacetate in vivo produces striatal cell damage

A variety of evidence suggests that the failure of cellular metabolism is one of the underlying causes of neurodegenerative diseases. For example, the inhibition of mitochondrial function produces a pattern of cellular pathology in the striatum that resembles that seen in Huntington's disease....

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Detalles Bibliográficos
Autores principales: Rodríguez, E, Rivera, I, Astorga, S, Mendoza, E, García, F, Hernández-Echeagaray, E
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862394/
https://www.ncbi.nlm.nih.gov/pubmed/20440403