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Isolated familial somatotropinoma: 11q13-loh and gene/protein expression analysis suggests a possible involvement of aip also in non-pituitary tumorigenesis

OBJECTIVE: Non-pituitary tumors have been reported in a subset of patients harboring germline mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene. However, no detailed investigations of non-pituitary tumors of AIP-mutated patients have been reported so far. PATIENTS: We examine...

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Detalles Bibliográficos
Autores principales: Toledo, Rodrigo A., Mendonca, Berenice B., Fragoso, Maria Candida B. V., Soares, Iberê C., Almeida, Madson Q., Moraes, Michelle B., Lourenço, Delmar M., Alves, Venâncio A. F., Bronstein, Marcello D., Toledo, Sergio P. A.
Formato: Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862671/
https://www.ncbi.nlm.nih.gov/pubmed/20454499
http://dx.doi.org/10.1590/S1807-59322010000400010