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Histone deacetylase inhibition results in a common metabolic profile associated with HT29 differentiation

Cell differentiation is an orderly process that begins with modifications in gene expression. This process is regulated by the acetylation state of histones. Removal of the acetyl groups of histones by specific enzymes (histone deacetylases, HDAC) usually downregulates expression of genes that can c...

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Detalles Bibliográficos
Autores principales: Alcarraz-Vizán, Gema, Boren, Joan, Lee, Wai-Nang Paul, Cascante, Marta
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862949/
https://www.ncbi.nlm.nih.gov/pubmed/20445757
http://dx.doi.org/10.1007/s11306-009-0192-0