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Histone deacetylase inhibition results in a common metabolic profile associated with HT29 differentiation
Cell differentiation is an orderly process that begins with modifications in gene expression. This process is regulated by the acetylation state of histones. Removal of the acetyl groups of histones by specific enzymes (histone deacetylases, HDAC) usually downregulates expression of genes that can c...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer US
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862949/ https://www.ncbi.nlm.nih.gov/pubmed/20445757 http://dx.doi.org/10.1007/s11306-009-0192-0 |