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Towards reliable isoform quantification using RNA-SEQ data
BACKGROUND: In eukaryotes, alternative splicing often generates multiple splice variants from a single gene. Here weexplore the use of RNA sequencing (RNA-Seq) datasets to address the isoform quantification problem. Given a set of known splice variants, the goal is to estimate the relative abundance...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863065/ https://www.ncbi.nlm.nih.gov/pubmed/20438653 http://dx.doi.org/10.1186/1471-2105-11-S3-S6 |