Neonatal mucosal immunization with a non-living, non-genetically modified Lactococcus lactis vaccine carrier induces systemic and local Th1-type immunity and protects against lethal bacterial infection

Safe and effective immunization of newborns and infants can significantly reduce childhood mortality, yet conventional vaccines have been largely unsuccessful in stimulating the neonatal immune system. We explored the capacity of a novel mucosal antigen delivery system consisting of non-living, non-...

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Detalles Bibliográficos
Autores principales: Ramirez, Karina, Ditamo, Yanina, Rodriguez, Liliana, Picking, Wendy L., van Roosmalen, Maarten L., Leenhouts, Kees, Pasetti, Marcela F.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863133/
https://www.ncbi.nlm.nih.gov/pubmed/19924118
http://dx.doi.org/10.1038/mi.2009.131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863133/
https://www.ncbi.nlm.nih.gov/pubmed/19924118
http://dx.doi.org/10.1038/mi.2009.131

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