C-terminal 37 residues of LRP promote the amyloidogenic processing of APP independent of FE65

The major defining pathological hallmark of Alzheimer's disease (AD) is the accumulation of amyloid β protein (Aβ), a small peptide derived from β- and γ-secretase cleavages of the amyloid precursor protein (APP). Recent studies have shown that the Low-density lipoprotein receptor-related prote...

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Detalles Bibliográficos
Autores principales: Lakshmana, Madepalli K, Chen, Eunice, Yoon, Il-Sang, Kang, David E
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864086/
https://www.ncbi.nlm.nih.gov/pubmed/18373737
http://dx.doi.org/10.1111/j.1582-4934.2008.00320.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864086/
https://www.ncbi.nlm.nih.gov/pubmed/18373737
http://dx.doi.org/10.1111/j.1582-4934.2008.00320.x

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