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Damaged DNA-binding protein 2 (DDB2) protects against UV irradiation in human cells and Drosophila

BACKGROUND: We observed previously that cisplatin-resistant HeLa cells were cross-resistant to UV light due to accumulation of DDB2, a protein implicated in DNA repair. More recently, we found that cFLIP, which represents an anti-apoptotic protein whose level is induced by DDB2, was implicated in pr...

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Detalles Bibliográficos
Autores principales: Sun, Nian-Kang, Sun, Chun-Ling, Lin, Chia-Hua, Pai, Li-Mai, Chao, Chuck CK
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864207/
https://www.ncbi.nlm.nih.gov/pubmed/20398405
http://dx.doi.org/10.1186/1423-0127-17-27