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PCBP-1 regulates alternative splicing of the CD44 gene and inhibits invasion in human hepatoma cell line HepG2 cells

BACKGROUND: PCBP1 (or alpha CP1 or hnRNP E1), a member of the PCBP family, is widely expressed in many human tissues and involved in regulation of transcription, transportation process, and function of RNA molecules. However, the role of PCBP1 in CD44 variants splicing still remains elusive. RESULTS...

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Detalles Bibliográficos
Autores principales: Zhang, Tong, Huang, Xian-Hong, Dong, Lan, Hu, Deqing, Ge, Changhui, Zhan, Yi-Qun, Xu, Wang-Xiang, Yu, Miao, Li, Wei, Wang, Xiaohui, Tang, Liujun, Li, Chang-Yan, Yang, Xiao-Ming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864215/
https://www.ncbi.nlm.nih.gov/pubmed/20361869
http://dx.doi.org/10.1186/1476-4598-9-72