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Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy

In recent years, tyrosine kinases (TKs) have been recognized as central players and regulators of cancer cell proliferation, apoptosis, and angiogenesis, and are therefore considered suitable potential targets for anti-cancer therapies. Several strategies for targeting TKs have been developed, the m...

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Detalles Bibliográficos
Autores principales: Sierra, J Rafael, Cepero, Virna, Giordano, Silvia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864216/
https://www.ncbi.nlm.nih.gov/pubmed/20385023
http://dx.doi.org/10.1186/1476-4598-9-75