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Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy
In recent years, tyrosine kinases (TKs) have been recognized as central players and regulators of cancer cell proliferation, apoptosis, and angiogenesis, and are therefore considered suitable potential targets for anti-cancer therapies. Several strategies for targeting TKs have been developed, the m...
Autores principales: | Sierra, J Rafael, Cepero, Virna, Giordano, Silvia |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864216/ https://www.ncbi.nlm.nih.gov/pubmed/20385023 http://dx.doi.org/10.1186/1476-4598-9-75 |
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