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Inhibiting miRNA in Caenorhabditis elegans using a potent and selective antisense reagent

BACKGROUND: Antisense reagents can serve as efficient and versatile tools for studying gene function by inhibiting nucleic acids in vivo. Antisense reagents have particular utility for the experimental manipulation of the activity of microRNAs (miRNAs), which are involved in the regulation of divers...

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Detalles Bibliográficos
Autores principales: Zheng, Genhua, Ambros, Victor, Li, Wen-hong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864223/
https://www.ncbi.nlm.nih.gov/pubmed/20359322
http://dx.doi.org/10.1186/1758-907X-1-9