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Major role for mRNA stability in shaping the kinetics of gene induction

BACKGROUND: mRNA levels in cells are determined by the relative rates of RNA production and degradation. Yet, to date, most analyses of gene expression profiles were focused on mechanisms which regulate transcription, while the role of mRNA stability in modulating transcriptional networks was to a l...

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Detalles Bibliográficos
Autores principales: Elkon, Ran, Zlotorynski, Eitan, Zeller, Karen I, Agami, Reuven
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864252/
https://www.ncbi.nlm.nih.gov/pubmed/20409322
http://dx.doi.org/10.1186/1471-2164-11-259