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Early administration of IL-6RA does not prevent radiation-induced lung injury in mice

BACKGROUND: Radiation pneumonia and subsequent radiation lung fibrosis are major dose-limiting complications for patients undergoing thoracic radiotherapy. Interleukin-6 (IL-6) is a pleiotropic cytokine and plays important roles in the regulation of immune response and inflammation. The purpose of t...

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Detalles Bibliográficos
Autores principales: Ogata, Toshiyuki, Yamazaki, Hideya, Teshima, Teruki, Kihara, Ayaka, Suzumoto, Yuko, Inoue, Takehiro, Nishimoto, Norihiro, Matsuura, Nariaki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864283/
https://www.ncbi.nlm.nih.gov/pubmed/20374625
http://dx.doi.org/10.1186/1748-717X-5-26