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BAFF Mediates Splenic B Cell Response and Antibody Production in Experimental Chagas Disease

BACKGROUND: B cells and antibodies are involved not only in controlling the spread of blood circulating Trypanosoma cruzi, but also in the autoreactive manifestations observed in Chagas disease. Acute infection results in polyclonal B cell activation associated with hypergammaglobulinemia, delayed s...

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Detalles Bibliográficos
Autores principales: Bermejo, Daniela A., Amezcua-Vesely, María C., Montes, Carolina L., Merino, María C., Gehrau, Ricardo C., Cejas, Hugo, Acosta-Rodríguez, Eva V., Gruppi, Adriana
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864296/
https://www.ncbi.nlm.nih.gov/pubmed/20454564
http://dx.doi.org/10.1371/journal.pntd.0000679