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Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies

BACKGROUND: Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)), an inflammatory enzyme expressed in atherosclerotic plaques, is a therapeutic target being assessed in trials of vascular disease prevention. We investigated associations of circulating Lp-PLA(2) mass and activity with risk of corona...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: Lancet Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864403/
https://www.ncbi.nlm.nih.gov/pubmed/20435228
http://dx.doi.org/10.1016/S0140-6736(10)60319-4