Development of a Cell-Based High-Throughput Assay to Screen for Inhibitors of Organic Anion Transporting Polypeptides 1B1 and 1B3

The two organic anion transporting polypeptides (OATPs) 1B1 and 1B3 are expressed at the sinusoidal membrane of hepatocytes. They have a broad and overlapping substrate specificity and transport many endobiotics and drugs. Specific inhibitors are required to determine the contribution of each OATP t...

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Detalles Bibliográficos
Autores principales: Gui, Chunshan, Obaidat, Amanda, Chaguturu, Rathnam, Hagenbuch, Bruno
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864424/
https://www.ncbi.nlm.nih.gov/pubmed/20448812
http://dx.doi.org/10.2174/1875397301004010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864424/
https://www.ncbi.nlm.nih.gov/pubmed/20448812
http://dx.doi.org/10.2174/1875397301004010001

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