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Troglitazone Reduces Glyoxalase I Protein Expression in Glioma and Potentiates the Effects of Chemotherapeutic Agents

Despite resistance of most gliomas to chemotherapy, approximately 2/3 of oligodendrogliomas show sensitivity to such agents. This sensitivity has been associated with deletions on chromosome 1p alone or in combination with 19q. Higher expression of the enzyme glyoxalase I has been found in oligodend...

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Detalles Bibliográficos
Autores principales: Helgager, Jeffrey, Li, Jie, Lubensky, Irina A., Lonser, Russell, Zhuang, Zhengping
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864507/
https://www.ncbi.nlm.nih.gov/pubmed/20454582
http://dx.doi.org/10.1155/2010/373491