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Troglitazone Reduces Glyoxalase I Protein Expression in Glioma and Potentiates the Effects of Chemotherapeutic Agents
Despite resistance of most gliomas to chemotherapy, approximately 2/3 of oligodendrogliomas show sensitivity to such agents. This sensitivity has been associated with deletions on chromosome 1p alone or in combination with 19q. Higher expression of the enzyme glyoxalase I has been found in oligodend...
Autores principales: | Helgager, Jeffrey, Li, Jie, Lubensky, Irina A., Lonser, Russell, Zhuang, Zhengping |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864507/ https://www.ncbi.nlm.nih.gov/pubmed/20454582 http://dx.doi.org/10.1155/2010/373491 |
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