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Dynamic Zebrafish Interactome Reveals Transcriptional Mechanisms of Dioxin Toxicity

BACKGROUND: In order to generate hypotheses regarding the mechanisms by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin) causes toxicity, we analyzed global gene expression changes in developing zebrafish embryos exposed to this potent toxicant in the context of a dynamic gene network. For this pu...

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Detalles Bibliográficos
Autores principales: Alexeyenko, Andrey, Wassenberg, Deena M., Lobenhofer, Edward K., Yen, Jerry, Linney, Elwood, Sonnhammer, Erik L. L., Meyer, Joel N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864754/
https://www.ncbi.nlm.nih.gov/pubmed/20463971
http://dx.doi.org/10.1371/journal.pone.0010465