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CFTR Depletion Results in Changes in Fatty Acid Composition and Promotes Lipogenesis in Intestinal Caco 2/15 Cells

BACKGROUND: Abnormal fatty acid composition (FA) in plasma and tissue lipids frequently occurs in homozygous and even in heterozygous carriers of cystic fibrosis transmembrane conductance regulator (CFTR) mutations. The mechanism(s) underlying these abnormalities remained, however, poorly understood...

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Detalles Bibliográficos
Autores principales: Mailhot, Geneviève, Rabasa-Lhoret, Rémi, Moreau, Alain, Berthiaume, Yves, Levy, Emile
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864762/
https://www.ncbi.nlm.nih.gov/pubmed/20463919
http://dx.doi.org/10.1371/journal.pone.0010446