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Phospholipase D1 Mediates TNFα-Induced Inflammation in a Murine Model of TNFα-Induced Peritonitis

BACKGROUND: Tumor Necrosis Factor alpha (TNFα) is a pleiotropic cytokine extensively studied for its role in the pathogenesis of a variety of disease conditions, including in inflammatory diseases. We have recently shown that, in vitro, that TNFα utilizes PLD1 to mediate the activation of NFκB and E...

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Detalles Bibliográficos
Autores principales: Sethu, Swaminathan, Pushparaj, Peter N., Melendez, Alirio J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864766/
https://www.ncbi.nlm.nih.gov/pubmed/20463923
http://dx.doi.org/10.1371/journal.pone.0010506