Comparative analysis of right element mutant lox sites on recombination efficiency in embryonic stem cells

BACKGROUND: Cre-mediated site-specific integrative recombination in mouse embryonic stem (ES) cells is a useful tool for genome engineering, allowing precise and repeated site-specific integration. To promote the integrative reaction, a left element/right element (LE/RE) mutant strategy using a pair...

Descripción completa

Detalles Bibliográficos
Autores principales: Araki, Kimi, Okada, Yuka, Araki, Masatake, Yamamura, Ken-ichi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Methodology article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865440/
https://www.ncbi.nlm.nih.gov/pubmed/20356367
http://dx.doi.org/10.1186/1472-6750-10-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865440/
https://www.ncbi.nlm.nih.gov/pubmed/20356367
http://dx.doi.org/10.1186/1472-6750-10-29

Ejemplares similares