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Intracerebroventricular injection of leukotriene B(4 )attenuates antigen-induced asthmatic response via BLT1 receptor stimulating HPA-axis in sensitized rats

BACKGROUND: Basic and clinical studies suggest that hypothalamic-pituitary-adrenal (HPA) axis is the neuroendocrine-immnue pathway that functionally regulates the chronic inflammatory disease including asthma. Our previous studies showed corresponding changes of cytokines and leukotriene B(4 )(LTB(4...

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Detalles Bibliográficos
Autores principales: Zhang, Shui-Juan, Deng, Yang-Mei, Zhu, Yi-Liang, Dong, Xin-Wei, Jiang, Jun-Xia, Xie, Qiang-Min
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865448/
https://www.ncbi.nlm.nih.gov/pubmed/20403205
http://dx.doi.org/10.1186/1465-9921-11-39