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Intracerebroventricular injection of leukotriene B(4 )attenuates antigen-induced asthmatic response via BLT1 receptor stimulating HPA-axis in sensitized rats
BACKGROUND: Basic and clinical studies suggest that hypothalamic-pituitary-adrenal (HPA) axis is the neuroendocrine-immnue pathway that functionally regulates the chronic inflammatory disease including asthma. Our previous studies showed corresponding changes of cytokines and leukotriene B(4 )(LTB(4...
Autores principales: | Zhang, Shui-Juan, Deng, Yang-Mei, Zhu, Yi-Liang, Dong, Xin-Wei, Jiang, Jun-Xia, Xie, Qiang-Min |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865448/ https://www.ncbi.nlm.nih.gov/pubmed/20403205 http://dx.doi.org/10.1186/1465-9921-11-39 |
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