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Effects of varying Notch1 signal strength on embryogenesis and vasculogenesis in compound mutant heterozygotes

BACKGROUND: Identifying developmental processes regulated by Notch1 can be addressed in part by characterizing mice with graded levels of Notch1 signaling strength. Here we examine development in embryos expressing various combinations of Notch1 mutant alleles. Mice homozygous for the hypomorphic No...

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Detalles Bibliográficos
Autores principales: Ge, Changhui, Stanley, Pamela
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865454/
https://www.ncbi.nlm.nih.gov/pubmed/20346184
http://dx.doi.org/10.1186/1471-213X-10-36