Phospholipase A(2 )inhibitors protect against prion and Aβ mediated synapse degeneration

BACKGROUND: An early event in the neuropathology of prion and Alzheimer's diseases is the loss of synapses and a corresponding reduction in the level of synaptophysin, a pre-synaptic membrane protein essential for neurotransmission. The molecular mechanisms involved in synapse degeneration in t...

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Detalles Bibliográficos
Autores principales: Bate, Clive, Tayebi, Mourad, Williams, Alun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865460/
https://www.ncbi.nlm.nih.gov/pubmed/20374666
http://dx.doi.org/10.1186/1750-1326-5-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865460/
https://www.ncbi.nlm.nih.gov/pubmed/20374666
http://dx.doi.org/10.1186/1750-1326-5-13

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