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Mutation Bias Favors Protein Folding Stability in the Evolution of Small Populations

Mutation bias in prokaryotes varies from extreme adenine and thymine (AT) in obligatory endosymbiotic or parasitic bacteria to extreme guanine and cytosine (GC), for instance in actinobacteria. GC mutation bias deeply influences the folding stability of proteins, making proteins on the average less...

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Detalles Bibliográficos
Autores principales: Mendez, Raul, Fritsche, Miriam, Porto, Markus, Bastolla, Ugo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865504/
https://www.ncbi.nlm.nih.gov/pubmed/20463869
http://dx.doi.org/10.1371/journal.pcbi.1000767