A MATE-Family Efflux Pump Rescues the Escherichia coli 8-Oxoguanine-Repair-Deficient Mutator Phenotype and Protects Against H(2)O(2) Killing

Hypermutation may accelerate bacterial evolution in the short-term. In the long-term, however, hypermutators (cells with an increased rate of mutation) can be expected to be at a disadvantage due to the accumulation of deleterious mutations. Therefore, in theory, hypermutators are doomed to extincti...

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Detalles Bibliográficos
Autores principales: Guelfo, Javier R., Rodríguez-Rojas, Alexandro, Matic, Ivan, Blázquez, Jesús
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865507/
https://www.ncbi.nlm.nih.gov/pubmed/20463878
http://dx.doi.org/10.1371/journal.pgen.1000931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865507/
https://www.ncbi.nlm.nih.gov/pubmed/20463878
http://dx.doi.org/10.1371/journal.pgen.1000931

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