Crystal Structure of HIV-1 gp41 Including Both Fusion Peptide and Membrane Proximal External Regions

The HIV-1 envelope glycoprotein (Env) composed of the receptor binding domain gp120 and the fusion protein subunit gp41 catalyzes virus entry and is a major target for therapeutic intervention and for neutralizing antibodies. Env interactions with cellular receptors trigger refolding of gp41, which...

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Detalles Bibliográficos
Autores principales: Buzon, Victor, Natrajan, Ganesh, Schibli, David, Campelo, Felix, Kozlov, Michael M., Weissenhorn, Winfried
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865522/
https://www.ncbi.nlm.nih.gov/pubmed/20463810
http://dx.doi.org/10.1371/journal.ppat.1000880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865522/
https://www.ncbi.nlm.nih.gov/pubmed/20463810
http://dx.doi.org/10.1371/journal.ppat.1000880

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