Prolonged Antigen Presentation Is Required for Optimal CD8+ T Cell Responses against Malaria Liver Stage Parasites

Immunization with irradiated sporozoites is currently the most effective vaccination strategy against liver stages of malaria parasites, yet the mechanisms underpinning the success of this approach are unknown. Here we show that the complete development of protective CD8+ T cell responses requires p...

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Detalles Bibliográficos
Autores principales: Cockburn, Ian A., Chen, Yun-Chi, Overstreet, Michael G., Lees, Jason R., van Rooijen, Nico, Farber, Donna L., Zavala, Fidel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865532/
https://www.ncbi.nlm.nih.gov/pubmed/20463809
http://dx.doi.org/10.1371/journal.ppat.1000877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865532/
https://www.ncbi.nlm.nih.gov/pubmed/20463809
http://dx.doi.org/10.1371/journal.ppat.1000877

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