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Rac1 Is Required for Epithelial Stem Cell Function during Dermal and Oral Mucosal Wound Healing but Not for Tissue Homeostasis in Mice

BACKGROUND: The regenerative capacity of the skin, including the continuous replacement of exfoliated cells and healing of injuries relies on the epidermal stem cells and their immediate cell descendants. The relative contribution of the hair follicle stem cells and the interfollicular stem cells to...

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Detalles Bibliográficos
Autores principales: Castilho, Rogerio M., Squarize, Cristiane H., Leelahavanichkul, Kantima, Zheng, Yi, Bugge, Thomas, Gutkind, J. Silvio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865533/
https://www.ncbi.nlm.nih.gov/pubmed/20463891
http://dx.doi.org/10.1371/journal.pone.0010503