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Host Genetics in Granuloma Formation: Human-Like Lung Pathology in Mice with Reciprocal Genetic Susceptibility to M. tuberculosis and M. avium

Development of lung granulomata is a hallmark of infections caused by virulent mycobacteria, reflecting both protective host response that restricts infection spreading and inflammatory pathology. The role of host genetics in granuloma formation is not well defined. Earlier we have shown that mice o...

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Detalles Bibliográficos
Autores principales: Kondratieva, Elena, Logunova, Nadya, Majorov, Konstantin, Averbakh, Mikhail, Apt, Alexander
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865535/
https://www.ncbi.nlm.nih.gov/pubmed/20463893
http://dx.doi.org/10.1371/journal.pone.0010515