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Concomitant Duplications of Opioid Peptide and Receptor Genes before the Origin of Jawed Vertebrates
BACKGROUND: The opioid system is involved in reward and pain mechanisms and consists in mammals of four receptors and several peptides. The peptides are derived from four prepropeptide genes, PENK, PDYN, PNOC and POMC, encoding enkephalins, dynorphins, orphanin/nociceptin and beta-endorphin, respect...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865548/ https://www.ncbi.nlm.nih.gov/pubmed/20463905 http://dx.doi.org/10.1371/journal.pone.0010512 |