Mutant p53 initiates a feedback loop that involves Egr-1/EGF receptor/ERK in prostate cancer cells

Early Growth Response-1 (Egr-1) is overexpressed in human prostate tumors and contributes to cancer progression. On the other hand, mutation of p53 is associated with advanced prostate cancer, as well as with metastasis and hormone independence. This study shows that in prostate cell lines in cultur...

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Detalles Bibliográficos
Autores principales: Sauer, Lysann, Gitenay, Delphine, Vo, Cassandra, Baron, Véronique T.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865566/
https://www.ncbi.nlm.nih.gov/pubmed/20190820
http://dx.doi.org/10.1038/onc.2010.24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865566/
https://www.ncbi.nlm.nih.gov/pubmed/20190820
http://dx.doi.org/10.1038/onc.2010.24

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