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Pathogenesis of natural goat scrapie: modulation by host PRNP genotype and effect of co-existent conditions

After detection of a high prevalence of scrapie in a large dairy goat herd, 72 infected animals were examined by immunohistochemistry with prion protein (PrP) antibody Bar224 to study the pathogenesis of the infection. Tissues examined included the brain and thoracic spinal cord (TSC), a wide select...

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Detalles Bibliográficos
Autores principales: González, Lorenzo, Martin, Stuart, Hawkins, Stephen A.C., Goldmann, Wilfred, Jeffrey, Martin, Sisó, Sílvia
Formato: Texto
Lenguaje:English
Publicado: EDP Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865875/
https://www.ncbi.nlm.nih.gov/pubmed/20374697
http://dx.doi.org/10.1051/vetres/2010020