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Mic1-3 Knockout Toxoplasma gondii is a good candidate for a vaccine against T. gondii-induced abortion in sheep

This study assessed the effectiveness of a mutant strain of Toxoplasma gondii (RH strain) lacking the mic1 and mic3 genes (Mic1-3KO) against Toxoplasma abortion in sheep. Ewes were inoculated subcutaneously with 10(5) Mic1-3KO tachyzoïtes in three independent experiments. Following vaccination, Mic1...

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Detalles Bibliográficos
Autores principales: Mévélec, Marie-Noëlle, Ducournau, Céline, Bassuny Ismael, Alaa, Olivier, Michel, Sèche, Édouard, Lebrun, Maryse, Bout, Daniel, Dimier-Poisson, Isabelle
Formato: Texto
Lenguaje:English
Publicado: EDP Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865876/
https://www.ncbi.nlm.nih.gov/pubmed/20385082
http://dx.doi.org/10.1051/vetres/2010021