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Extranuclear Estrogen Receptors Mediate the Neuroprotective Effects of Estrogen in the Rat Hippocampus

BACKGROUND: 17β-estradiol (E2) has been implicated to exert neuroprotective effects in the brain following cerebral ischemia. Classically, E2 is thought to exert its effects via genomic signaling mediated by interaction with nuclear estrogen receptors. However, the role and contribution of extranucl...

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Detalles Bibliográficos
Autores principales: Yang, Li-cai, Zhang, Quan-Guang, Zhou, Cai-feng, Yang, Fang, Zhang, Yi-dong, Wang, Rui-min, Brann, Darrell W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866326/
https://www.ncbi.nlm.nih.gov/pubmed/20479872
http://dx.doi.org/10.1371/journal.pone.0009851