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HPLC Method for Simultaneous Determination of Impurities and Degradation Products in Zonisamide

A gradient reversed phase HPLC method was developed and validated for the analysis of related substances in zonisamide (1,2-benzisoxazole-3-methanesulfonamide), using a Waters Symmetry C8 (150*3.9 mm) column with a flow rate of 1.0 ml/min and detection at 280 nm. The mobile phase component A consist...

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Detalles Bibliográficos
Autores principales: Vijayakumar, E. K. S., Dhore, D. M., Kumar, M.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866343/
https://www.ncbi.nlm.nih.gov/pubmed/20502570
http://dx.doi.org/10.4103/0250-474X.58183