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The Outer Vestibule of the Na(+) Channel–Toxin Receptor and Modulator of Permeation as Well as Gating
The outer vestibule of voltage-gated Na(+) channels is formed by extracellular loops connecting the S5 and S6 segments of all four domains (“P-loops”), which fold back into the membrane. Classically, this structure has been implicated in the control of ion permeation and in toxin blockage. However,...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Molecular Diversity Preservation International
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866490/ https://www.ncbi.nlm.nih.gov/pubmed/20479982 http://dx.doi.org/10.3390/md8041373 |