Molecular Structure and Dimeric Organization of the Notch Extracellular Domain as Revealed by Electron Microscopy

BACKGROUND: The Notch receptor links cell fate decisions of one cell to that of the immediate cellular neighbor. In humans, malfunction of Notch signaling results in diseases and congenital disorders. Structural information is essential for gaining insight into the mechanism of the receptor as well...

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Detalles Bibliográficos
Autores principales: Kelly, Deborah F., Lake, Robert J., Middelkoop, Teije C., Fan, Hua-Ying, Artavanis-Tsakonas, Spyros, Walz, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866536/
https://www.ncbi.nlm.nih.gov/pubmed/20479883
http://dx.doi.org/10.1371/journal.pone.0010532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866536/
https://www.ncbi.nlm.nih.gov/pubmed/20479883
http://dx.doi.org/10.1371/journal.pone.0010532

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