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Acute effects of the sigma-2 receptor agonist siramesine on lysosomal and extra-lysosomal proteolytic systems in lens epithelial cells

PURPOSE: The aim of the present study was to examine the effects of the sigma-2 receptor agonist, siramesine, on morphology, growth, cell death, lysosomal function, and effects on extra-lysosomal proteolytic systems in human lens epithelial cells. METHODS: Human lens epithelial cells in culture were...

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Detalles Bibliográficos
Autores principales: Jonhede, S., Petersen, A., Zetterberg, M., Karlsson, J-O.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866574/
https://www.ncbi.nlm.nih.gov/pubmed/20461150