Evidence for an Essential Deglycosylation-Independent Activity of PNGase in Drosophila melanogaster

BACKGROUND: Peptide:N-glycanase (PNGase) is an enzyme which releases N-linked glycans from glycopeptides/glycoproteins. This enzyme plays a role in the ER-associated degradation (ERAD) pathway in yeast and mice, but the biological importance of this activity remains unknown. PRINCIPAL FINDINGS: In t...

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Detalles Bibliográficos
Autores principales: Funakoshi, Yoko, Negishi, Yuki, Gergen, J. Peter, Seino, Junichi, Ishii, Kumiko, Lennarz, William J., Matsuo, Ichiro, Ito, Yukishige, Taniguchi, Naoyuki, Suzuki, Tadashi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866665/
https://www.ncbi.nlm.nih.gov/pubmed/20479940
http://dx.doi.org/10.1371/journal.pone.0010545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866665/
https://www.ncbi.nlm.nih.gov/pubmed/20479940
http://dx.doi.org/10.1371/journal.pone.0010545

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