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Modulation of IL-17 and Foxp3 Expression in the Prevention of Autoimmune Arthritis in Mice

BACKGROUND: Rheumatoid Arthritis (RA) is a chronic immune mediated disease associated with deregulation of many cell types. It has been reported that different T cell subsets have opposite effects in disease pathogenesis, in particular Th17 and Treg cells. METHODOLOGY AND FINDINGS: We investigated w...

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Detalles Bibliográficos
Autores principales: Duarte, Joana, Agua-Doce, Ana, Oliveira, Vanessa G., Fonseca, João Eurico, Graca, Luis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866666/
https://www.ncbi.nlm.nih.gov/pubmed/20479941
http://dx.doi.org/10.1371/journal.pone.0010558