Mitochondrial Superoxide Contributes to Blood Flow and Axonal Transport Deficits in the Tg2576 Mouse Model of Alzheimer's Disease

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disease characterized by the progressive decline in cognitive functions and the deposition of aggregated amyloid β (Aβ) into senile plaques and the protein tau into tangles. In addition, a general state of oxidation has long been known...

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Detalles Bibliográficos
Autores principales: Massaad, Cynthia A., Amin, Samir K., Hu, Lingyun, Mei, Yuan, Klann, Eric, Pautler, Robia G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866668/
https://www.ncbi.nlm.nih.gov/pubmed/20479943
http://dx.doi.org/10.1371/journal.pone.0010561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866668/
https://www.ncbi.nlm.nih.gov/pubmed/20479943
http://dx.doi.org/10.1371/journal.pone.0010561

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