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Arsenic Inhibits Neurite Outgrowth by Inhibiting the LKB1–AMPK Signaling Pathway

BACKGROUND: Arsenic (As) is an environmental pollutant that induces numerous pathological effects, including neurodevelopmental disorders. OBJECTIVES AND METHODS: We evaluated the role of the LKB1–AMPK pathway in As-induced developmental neurotoxicity using Neuro-2a (N2a) neuroblastoma cells as a mo...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Meng, Dan, Chang, Qingshan, Pan, Jingju, Zhang, Zhuo, Chen, Gang, Ke, Zunji, Luo, Jia, Shi, Xianglin
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866677/
https://www.ncbi.nlm.nih.gov/pubmed/20439172
http://dx.doi.org/10.1289/ehp.0901510